Detalhe da pesquisa
1.
DRG afferents that mediate physiologic and pathologic mechanosensation from the distal colon.
Cell
; 186(16): 3368-3385.e18, 2023 08 03.
Artigo
Inglês
| MEDLINE | ID: mdl-37541195
2.
mTORC1 Activator SLC38A9 Is Required to Efflux Essential Amino Acids from Lysosomes and Use Protein as a Nutrient.
Cell
; 171(3): 642-654.e12, 2017 Oct 19.
Artigo
Inglês
| MEDLINE | ID: mdl-29053970
3.
Nutrient-sensing mechanisms across evolution.
Cell
; 161(1): 67-83, 2015 Mar 26.
Artigo
Inglês
| MEDLINE | ID: mdl-25815986
4.
Parallel ascending spinal pathways for affective touch and pain.
Nature
; 587(7833): 258-263, 2020 11.
Artigo
Inglês
| MEDLINE | ID: mdl-33116307
5.
KICSTOR recruits GATOR1 to the lysosome and is necessary for nutrients to regulate mTORC1.
Nature
; 543(7645): 438-442, 2017 03 16.
Artigo
Inglês
| MEDLINE | ID: mdl-28199306
6.
Regulation of mTORC1 by the Rag GTPases is necessary for neonatal autophagy and survival.
Nature
; 493(7434): 679-83, 2013 Jan 31.
Artigo
Inglês
| MEDLINE | ID: mdl-23263183
7.
A mouse model of DEPDC5-related epilepsy: Neuronal loss of Depdc5 causes dysplastic and ectopic neurons, increased mTOR signaling, and seizure susceptibility.
Neurobiol Dis
; 111: 91-101, 2018 03.
Artigo
Inglês
| MEDLINE | ID: mdl-29274432
8.
Clinical Impact of Tumor Mutational Burden in Neuroblastoma.
J Natl Cancer Inst
; 111(7): 695-699, 2019 07 01.
Artigo
Inglês
| MEDLINE | ID: mdl-30307503
9.
The Dawn of the Age of Amino Acid Sensors for the mTORC1 Pathway.
Cell Metab
; 26(2): 301-309, 2017 Aug 01.
Artigo
Inglês
| MEDLINE | ID: mdl-28768171
10.
Structural basis for leucine sensing by the Sestrin2-mTORC1 pathway.
Science
; 351(6268): 53-8, 2016 Jan 01.
Artigo
Inglês
| MEDLINE | ID: mdl-26586190
11.
Sestrin2 is a leucine sensor for the mTORC1 pathway.
Science
; 351(6268): 43-8, 2016 Jan 01.
Artigo
Inglês
| MEDLINE | ID: mdl-26449471
12.
Recurrent mTORC1-activating RRAGC mutations in follicular lymphoma.
Nat Genet
; 48(2): 183-8, 2016 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-26691987
13.
Metabolism. Lysosomal amino acid transporter SLC38A9 signals arginine sufficiency to mTORC1.
Science
; 347(6218): 188-94, 2015 Jan 09.
Artigo
Inglês
| MEDLINE | ID: mdl-25567906
14.
The Sestrins interact with GATOR2 to negatively regulate the amino-acid-sensing pathway upstream of mTORC1.
Cell Rep
; 9(1): 1-8, 2014 Oct 09.
Artigo
Inglês
| MEDLINE | ID: mdl-25263562
15.
Corrigendum: Recurrent mTORC1-activating RRAGC mutations in follicular lymphoma.
Nat Genet
; 48(6): 700, 2016 05 27.
Artigo
Inglês
| MEDLINE | ID: mdl-27230687